MTU
The largest packet a link carries in one piece; BLE has its own, smaller one.
The maximum transmission unit caps the payload of one link-layer frame, 1,500 bytes of IP packet on Ethernet and Wi-Fi, so bigger messages are split. BLE's ATT MTU caps the payload of one attribute operation (23 bytes by default, negotiable upward), which together with the connection interval limits throughput.
Examples
Ethernet and Wi-Fi have an MTU of 1,500 bytes, so a 2,000-byte message crosses them as at least two packets.
With BLE's default MTU of 23 bytes, a notification carries at most 20 bytes of value.
Negotiating an MTU of 247 lets one notification carry 244 bytes, enough for 40 accelerometer samples.
See also